湖南省岳阳市癫痫流行病学调查

Epidemiological survey of epilepsy in Yueyang of Hunan Province

摘要:

目的 了解湖南岳阳癫痫患病率及治疗缺口，为开展防治工作提供依据。方法 采用多级整群随机抽样方法确定调查人群，运用WHO建议的癫痫流行病学专项调查问卷，采用国际统一的癫痫诊断标准，由经过统一培训的调查员入户调查，调查确诊或可疑为癫痫者均经神经科医师再次访查确诊。结果 共调查32059人，确诊癫痫患者143例，癫痫患病率为4.5‰。男性患病率高于女性（P<0.05）。年龄组患病率分布存在20岁年龄组（8.4‰）和60岁年龄组（5.4‰）两个高峰。农村患病率明显高于城市（P<0.05）。继发全面性强直-阵挛发作占大多数（63.4%）。活动性癫痫的治疗缺口93.4%。结论 湖南岳阳癫痫患病率农村地区较高、城市较低，患者中约有90%以上没有得到正确的治疗，应尽快制定合理的干预对策。

Abstract:

Objective To understand the prevalence rate, and treatment gap of epilepsy in Yueyang of Hunan Province.Methods A door-to-door epidemiological survey on epilepsy was conducted by random cluster sampling among the urban and rural populations of Yueyang, Hunan Province, China. The screening questionnaire for epilepsy used in this study was adapted from the WHO and ICBERG standard screening questionnaire. The persons diagnosed or suspected as epilepsy during screening were followed up by neurologists.Results A total of 32059 persons were investigated. One hundred and forty-three persons were diagnosed with epilepsy, with a prevalence rate of 4.5‰. Prevalence rate of epilepsy was higher in males than in females and it was higher in rural areas than in urban areas. Two peak prevalences of epilepsy were found in 20-(8.4%) and 60-year-old groups(5.4%). Secondary generalized tonic-clonic seizure prevailed over other seizure types in frequency(63.4%). 93.4% of the patients with active epilepsy did not receive standard and regular antiepileptic treatments.Conclusions The prevalence rate of epilepsy in rural areas is higher than in urbans in Yueyang of Hunan Province. The large amount of patients with treatment gaps indicates an urgent need for a rational intervention strategy.