脑卒中后癫痫再发的临床分析

Clinical analysis of reappearance of post-stroke epilepsy：a case-control study

摘要:

目的 分析脑卒中后癫痫的临床特点，探讨卒中后癫痫再发的影响因素。方法 回顾性分析43例脑卒中后癫痫患者的临床资料，与49例脑卒中未合并癫痫者进行比较。采用logistic二分类回归分析癫痫再发的可能影响因素。结果 卒中后癫痫多见于大面积脑梗死和蛛网膜下腔出血者（P<0.05）；回归分析发现癫痫再发与患者合并冠心病有关（P<0.05）。结论 大面积脑梗死和蛛网膜下腔出血后易并发癫痫，冠心病与脑卒中后癫痫再发有关。

Abstract:

Objective To study clinical features and factors of reappearance for post-stroke epilepsy.Methods Clinical data of forty-three patients with epilepsy caused by cerebral apoplexy were retrospectively studied and compared the clinical features of 49 cases of controls without epilepsy reappeararce. Regression analysis was used for studying the factors for reappearance of post-stroke epilepy.Results Post-stroke epilepsy was common in patients with large area of cerebral infarction and subarachnoid hemorrhage (P<0.05). Regression analysis demonstrated that the presense of coronary artery disease was related with the recurrence of epilepsy (P<0.05).Conclusions Epilepsy may occur frequently following a large area of cerebral infarction and subarachnoid hemorrhage. Coronary artery disease may be related to reappearance of post-stroke epilepsy.