海马MRI提示为海马硬化的颞叶癫痫患者的术后随访

To observe operative effecacy of the temporal lobe epilepsy(TLE)with hippocampal sclerosis(HS)

摘要:

目的 观察磁共振上提示有海马硬化的颞叶癫痫患者的手术疗效。方法 术后电话及定期复查脑电图对磁共振提示为海马硬化且经病理证实为海马硬化的患者进行随访，至少随访两年的患者纳入实验，随访结果采用统计软件SPSS 17.0进行统计分析，定性资料的比较，选择卡方检验，以P<0.05为有统计学意义，分析术后癫痫控制的情况。结果 对于有海马硬化的患者，与发作间期异常放电一致均有满意的手术效果；对于影像学上有明显海马硬化的患者术后6年内随访发现癫痫有效率分别为90.66%，88.57%，88.25%，86.20%，72%，69.04%，差异有统计学意义。结论 手术是治疗伴有海马硬化的颞叶癫痫的有效方法，一旦影像学上提示海马硬化，且脑电图监测能够定侧的颞叶癫痫，应该及早手术。

Abstract:

Objective To observe the operative effecacy in patients with medically intractable TLE associated with HS, by Magnetic Resonance Imaging. Methods Selecting patients with MRI revealed HS and ascertained Histopathologically followed at least 2 years by phone or checking electroencephalogram regularly included in this experiment, analyzing consequence by using spss 17.0 systerms.Results Patients with HS and interictal epileptic discharges were congruenctic obvious operation result and in the following 6 years patients were satisfied with the operation were 90.66%,88.57%,88.25%,86.20%,72%,69.04% respectively. Conclusions The anterior temporal lobectomy should be performed in the patients with TLE accompanied with HS, if the EEG shows that there are epileptic discharges in the ipsilateral temporal lobe.