非手术治疗自发性基底节区脑出血预后因素分析

Prognostic factors of analysis on patients with nonoperative treatment of intracerebral hemorrhage in basal ganglia

摘要:

目的 探讨非手术治疗自发性基底节区出血预后相关的因素。方法 回顾性分析贵阳市第二人民医院神经外科2005年4月至2012年6月收治的109例随访资料完整的患者,采用Kaplan-Meier法进行单因素分析。Log-rank法进行生存率显著性检验,Cox比例风险回归模型作多因素分析。结果 单因素分析显示入院时GOS评分、GCS评分、高血压、出血量、出血破入脑室、肺部感染及血糖与预后有关联。多因素分析显示GCS评分、出血量和血糖是自发性基底节区出血预后相关的独立危险因素。结论 发病时GCS评分、出血量和血糖水平是影响患者预后的重要因素。

Abstract:

Objective To investigate the factors influencing prognosis of nonoperative treatment of intracerebral hemorrhage in basal ganglia.Methods The clinical data and survival status of 109 patients with intracerebral hemorrhage in basal ganglia who were admitted to Neurosurgery of Guiyang Second People's Hospital during the period from April 2005 to June 2012 were reviewed retrospectively. The survival analysis was analyzed with Kaplan-Meier method. The univariate analysis was used to determine the prognositic factors related with survival rate by Log-rank test. Multivariate factors for the survival rates were analyzed using the Cox proportional hazards regression model.Results Univariate analysis revealed that GOS scale, GCS scale, hypertension, hemorrhage volume, intraventricular hemorrhage, pulmonary infection and glucose were the factors influencing prognostic factors of hypertensive brainstem hemorrhage. Multivariate analysis showed that GCS scale, hemorrhage volume and glucose were independent prognostic factors.Conclusions GCS scale, hemorrhage volume and glucose were important prognostic factors of intracerebral hemorrhage in basal ganglia.