21例脑室内中枢神经细胞瘤的临床分析

Clinical analysis of 21 cases of intraventricular neurocytoma

摘要:

目的 探讨脑室内中枢神经细胞瘤的临床特征和治疗方法。方法 回顾性分析2009.10至2014.5收治的21例脑室内中枢神经细胞瘤患者的临床资料。结果 其主要临床表现为头痛、呕吐、视力下降及视乳头水肿。全部病例均行显微手术治疗, 肿瘤全切除17例, 次全切除4例。21例随访患者, KPS>80分者17例, 60~80分3例, <60分1例。结论 脑室内中枢神经细胞瘤的临床表现和影像学无特异性, 确诊需依靠病理检查;该病首选显微手术切除, 次全切除患者术后应行辅助放疗;Brainlab神经导航结合术中使用管状脑牵开器(VBAS)能提高肿瘤的切除程度, 有效减少手术创伤与围手术期并发症, 改善患者术后生活质量。

Abstract:

Objective To investigate the clinical features and treatment of the intraventricula rneurocytoma.Methods The clinical data of 21 patients with intraventricular neurocytoma, who underwent microsurgery from October 2009 to May 2014, were analyzed retrospectively.Results The major clinic signs included: headache, vomiting, decreased vision and visual papillary edema.Of all the cases, 17 were total resection and 4sub-totally resection under surgical microscope.Among the effective follow-ups of 21 cases, KPS > 80 in 17 cases, 3 cases between 60 and 80, and 1 below 60.Conclusions The clinical manifestations and radiological features of the intraventricular neurocytoma were not specific, the diagnoses were made by pathology.Microsurgery is the preferred treatment for the disease.