基于3D Slicer软件探讨高血压脑出血血肿体积诊断的准确性

An investigation of the accuracy of hematoma volume measurement in hypertensive intracranial hemorrhage based on 3D Slicer

摘要:

目的 评估CT诊断报告中关于高血压脑出血血肿体积统计的准确性。方法 回顾性分析117例高血压脑出血患者头颅CT影像科报告，调取CT扫描原始数据后运用3D Slicer软件进行脑内血肿三维结构重建，精确统计血肿体积；依据软件计算血肿体积大小分组与影像科CT诊断报告进行统计比对，评估影像科统计血肿体积的偏差程度。结果 117例高血压脑出血头颅CT扫描原始数据运用3D Slicer软件进行三维重建并体积计算均可在较短时间内完成（用时最长242.4 s；最短21.98 s；平均78.57±40.91 s），其中最小出血量为0.62 ml；最大出血量为166.03 ml；平均出血量为33.79±3.12 ml；影像诊断报告中最小出血量为1 ml；最大出血量为190 ml；平均37.66±3.48 ml；两者有显著性差异，且差异程度与血肿量大小无明显相关性。结论 基于3D Slicer软件可以在较短时间内实现血肿三维结构重建并较准确统计血肿体积，操作简便易行，可以为高血压脑出血治疗策略的选择提供客观准确的血肿量依据。

Abstract:

Objective To evaluate the accuracy of hematoma volume measurement using computed tomography (CT) reports in hypertensive intracerebral hemorrhage (HICH).Methods The head CT reports of 117 HICH patients were retrospectively analyzed. After collecting the raw scan data, 3D Slicer was used to reconstruct the three-dimensional (3D) structure of intracerebral hematoma and accurately calculate the hematoma volume. The size of hematoma calculated by 3D Slicer was grouped and statistically compared with that in CT reports to evaluate the deviation of hematoma volume in the department of radiology.Results With 3D Slicer, both 3D reconstruction and volume calculation of the raw head CT scan data of the 117 HICH patients were finished in a short time (range 21.98-242.4 s, mean 78.57±40.91 s); the amount of bleeding ranged from 0.62 ml to 166.03 ml, with a mean of 33.79±3.12 ml. In contrast, according to the CT reports, the amount of bleeding ranged from 1 ml to 190 ml, with a mean of 37.66±3.48 ml. There was a significant difference between the results of the two measurement methods, and the degree of deviation was not significantly correlated with hematoma volume.Conclusions With 3D Slicer, 3D reconstruction of hematoma and accurate calculation of its volume can be finished in a short time, and the operation is simple and easy. It can provide an accurate hematoma volume basis for the selection of therapeutic strategy for HICH.