高压氧联合阿托伐他汀治疗慢性硬脑膜下血肿116例疗效分析

Efficacy of hyperbaric oxygen combined with atorvastatin for the treatment of chronic subdural hematoma: An analysis of 116 cases

摘要:

目的 探讨高压氧联合阿托伐他汀在慢性硬脑膜下血肿保守治疗中的效果。方法 回顾性分析2015年3月—2018年3月解放军第九八七医院、宝鸡市高新人民医院及宝鸡市第三人民医院共收治的116例行系统高压氧联合阿托伐他汀治疗的慢性硬脑膜下血肿患者（A组），并与2012年2月—2015年2月三所医院共收治的122例行常规保守治疗的慢性硬脑膜下血肿患者（B组）的治疗结果进行比较。结果 A组和B组患者经保守治疗成功、病情好转例数分别为104例（89.66%）、66例（54.10%），平均治疗费用分别为（8523.65±717.85）及（9723.26±1534.85）元，治疗满意度分别为87.07%（101例）、70.49%（86例）。其中两组患者治疗好转率及治疗满意度比较，差异有统计学意义（P＜0.05）。结论 高压氧联合阿托伐他汀治疗，可提高慢性硬脑膜下血肿保守治疗的病情好转率，提高患者的治疗体验满意度，并可降低平均治疗费用。

Abstract:

Objective To investigate the efficacy of hyperbaric oxygen combined with atorvastatin in the conservative treatment of chronic subdural hematoma.Methods A retrospective analysis was performed on the clinical data of 116 patients with chronic subdural hematoma who were admitted to No. 987 Hospital of the PLA Joint Logistics Support Force, Baoji High-tech People's Hospital, and The Third People's Hospital of Baoji City and systematically treated with hyperbaric oxygen combined with atorvastatin from March 2015 to March 2018 (group A); and the treatment outcome of group A was compared with that of 122 patients with chronic subdural hematoma who were admitted to these three hospitals and received conventional conservative treatment from February 2012 to February 2015 (group B).Results A total of 104 patients (89.66%) in group A and 66 patients (54.10%) in group B were successfully treated with conservative treatment and achieved improvements in their conditions. The mean cost of treatment was 8523.65±717.85 yuan in group A and 9723.26±1534.85 yuan in group B. The degree of satisfaction was 87.07% (101 patients) in group A and 70.49% (86 patients) in group B. There were significant differences in patients' improvement rate and degree of satisfaction between the two groups (both P<0.05).Conclusions Systematic hyperbaric oxygen combined with atorvastatin treatment can increase the improvement rate of patients with chronic subdural hematoma in the conservative treatment, improve the degree of patients' satisfaction with the treatment, and reduce the mean cost of treatment.