儿童室管膜瘤的临床研究进展

Progress in clinical research on childhood ependymoma

摘要:

室管膜瘤是一种原发于神经上皮的中枢神经系统肿瘤，病变累及脑和脊髓，多发于儿童。基因分型的新分类方法，为室管膜瘤的治疗和预后评估提供了更为可靠的依据。室管膜瘤对辅助治疗的敏感性低是造成患儿预后较差的重要原因之一。该文对近年来儿童室管膜瘤的分型、诊断、治疗策略等进行综述。

Abstract:

Ependymomas are neuroepithelial tumors arising throughout all compartments of the central nervous system involving the intracranial and spine, and predominantly occur in children.The new genomic profile system led to a more precise evaluation for the treatment and prognosis of ependymoma.The low sensitivity of ependymoma to adjuvant therapy is one of the important reasons for the poor prognosis of children.This article reviews the classification, diagnosis, and treatment strategies of childhood ependymoma in recent years.