认知障碍患者个体化智能康复训练技术规范

Technical specifications for individualized intelligent rehabilitation therapy for patients with cognitive impairment

摘要:

阿尔茨海默病(AD)是以进行性认知障碍为主要表现的神经变性疾病，伴有日常活动能力损害和人格变化，给家庭和社会带来了严重的负担。轻度认知障碍(MCI)是一组介于健康老化和AD之间的过渡状态。目前的抗认知障碍药物治疗效果不佳，在有效的药物干预上市之前，应积极探索有效的非药物干预方法。越来越多的证据表明，认知干预能够有效改善AD病变引起的认知功能损伤，亦能够用于健康老年人预防AD的发生。在该文中，总结了认知干预的相关研究及可能机制，对未来认知干预的应用提出了建议，并形成了认知障碍患者个体化智能康复治疗的技术规范。

Abstract:

Alzheimer’s disease （AD） is a neurodegenerative disease characterized by progressive cognitive impairment， impairment of daily activities， and personality changes， which brings a heavy burden on families and society. Mild cognitive impairment （MCI） is the transition stage between healthy aging and AD. Current pharmacotherapy for cognitive impairment has an unsatisfactory clinical effect， and effective non-pharmaceutical interventions should be actively explored before the marketing of effective pharmaceutical interventions. An increasing number of evidence has shown that cognitive interventions can effectively alleviate cognitive impairment caused by AD and may also be used to prevent the development of AD in healthy elderly people. This article summarizes related studies and possible mechanisms of cognitive intervention， provides suggestions for the future application of cognitive intervention， and develops the technical specifications for individualized intelligent rehabilitation therapy for patients with cognitive impairment.