1990年与2016年湖北省人群脑肿瘤疾病负担分析

Disease burden of brain tumor in the population of Hubei province of China in 1990 and 2016

摘要:

目的 分析1990年与2016年湖北省人群归因于脑肿瘤的疾病负担。方法 利用2016年全球疾病负担研究结果，采用标化发病率、标化死亡率、过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY)等指标，对湖北省人群脑肿瘤的疾病负担情况进行描述，并通过计算1990年与2016年相应指标的变化幅度，分析湖北省脑肿瘤疾病负担的变化情况。结果 湖北省人群脑肿瘤的标化发病率从1990年的5.16/10万增至2016年的10.25/10万，增加98.64%。标化死亡率从1990年的5.48/10万减至2016年的4.95/10万，减少9.67%。标化YLL率从1990年的181.93/10万降至2016年的141.50/10万，降低22.22%。标化YLD率从1990年的1.64/10万升至2016年的3.39/10万，增加106.49%。标化DALY率从1990年的183.57/10万降至2016年的144.89/10万，降低21.07%。与1990年相比，男性的YLL、YLD以及DALY和女性的YLD均有所上升，且每个年龄段的男性标化死亡率和标化DALY率均不低于女性。结论 与1990年相比，2016年湖北省人群脑肿瘤死亡造成的疾病负担仍较为严重，脑肿瘤在男性和女性群体中所造成的疾病负担水平有差异。

Abstract:

Objective To investigate the disease burden of brain tumor in the population of Hubei province of China in 1990 and 2016.Methods With reference to the results of 2016 Global Burden of Disease Study， the indicators including standardized incidence rate， standardized mortality rate， years of life lost （YLL） due to premature death， years lived with disability （YLD）， and disability-adjusted life years （DALY） were used to describe the disease burden of brain tumor in the population of Hubei province， and the changes in each indicator from 1990 to 2016 were used to describe the change in the disease burden of brain tumor in Hubei province.Results In Hubei province from 1990 to 2016， the standardized incidence rate of brain tumor increased from 5.16/100 000 to 10.25/100 000 （increased by 98.64%）， the standardized mortality rate of brain tumor decreased from 5.48/100 000 to 4.95/100 000 （decreased by 9.67%）， the standardized YLL rate decreased from 181.93/100 000 to 141.50/100 000 （decreased by 22.22%）， the standardized YLD rate increased from 1.64/100 000 to 3.39/100 000 （increased by 106.49%）， and the standardized DALY rate decreased from 183.57/100 000 to 144.89/100 000 （decreased by 21.07%）. From 1990 to 2016， there were increases in YLL， YLD， and DALY for the male population and in YLD for the female population， and the standardized mortality rate and standardized DALY rate of the male population in each age group were not lower than those of the female population.Conclusions Compared with 1990， the disease burden caused by brain tumor in Hubei province is still serious in 2016， and there is a difference in the disease burden caused by brain tumor between the male population and the female population.