成人弥漫性低级别胶质瘤相关性癫痫发生机制与治疗的研究进展

Research advances in the pathogenesis and treatment of diffuse low-grade glioma-related epilepsy in adults

摘要:

癫痫是成人幕上弥漫性低级别胶质瘤(DLGG)最常见的临床症状，常常影响着DLGG患者的生活质量，致残致死率高。控制癫痫发作对于改善DLGG患者的生存质量尤为重要。该文总结了弥漫性低级别胶质瘤相关性癫痫的发作特点、发生机制及治疗方法，以期为弥漫性低级别胶质瘤相关性癫痫患者的个体化临床诊疗决策提供依据。

Abstract:

Epilepsy is the most common clinical symptom of supratentorial diffuse low-grade glioma （DLGG） in adults， which often affects the quality of life of DLGG patients and increases the disability rate and mortality rate. Control of seizures is particularly important to improve quality of life in patients with DLGG. This article summarizes the characteristics， pathogenesis， and treatment of DLGG-related epilepsy， in order to provide a basis for the individualized clinical diagnosis and treatment of patients with DLGG-related epilepsy.