垂体腺瘤卒中危险因素分析

Risk factors for pituitary adenoma apoplexy

摘要:

目的 分析垂体腺瘤卒中的危险因素。方法 选取2020年6月—2021年12月中南大学湘雅医院诊治的50例垂体腺瘤患者，根据影像及手术资料分为垂体瘤合并卒中组（23例）和垂体瘤不合并卒中组（27例），分析卒中因素。结果 多因素Logistic分析显示垂体瘤手术切除史、垂体瘤最大直径大是其影响因素。其中有1例伽玛刀治疗后出现肿瘤亚临床卒中的特殊病例。结论 有垂体瘤手术切除史、垂体瘤最大直径大的患者是发生卒中的高危因素，伽玛刀治疗后出现影像学上的肿胀，可能是亚临床卒中。

Abstract:

Objective To investigate the risk factors for pituitary adenoma apoplexy.Methods A total of 50 patients with pituitary adenoma who were treated in Xiangya Hospital of Central South University from June 2020 to December 2021 were enrolled in the study， and according to imaging and surgical data， they were divided into pituitary adenoma with apoplexy group with 23 patients and pituitary adenoma without apoplexy group with 27 patients. The risk factors for apoplexy were observed and analyzed.Results The multivariate logistic regression analysis showed that history of surgical resection of pituitary adenoma and the maximum diameter of pituitary adenoma were related influencing factors. Among these patients， 1 patient experienced subclinical apoplexy due to tumor after gamma knife treatment.Conclusion History of surgical resection of pituitary adenoma and the maximum diameter of pituitary adenoma are the high-risk factors for pituitary adenoma apoplexy， and swelling after gamma knife may suggest subclinical apoplexy.