微生物菌群在胶质瘤中的研究进展

Research advances in microbial flora in glioma

摘要:

胶质瘤与肠道微生物菌群相关的研究近年来逐渐崭露头角，亦有研究发现胶质瘤中存在肿瘤内微生物菌群。尽管已有研究揭示了肠道微生物菌群可能通过免疫调节、表观遗传修饰等途径对胶质瘤产生影响，但具体机制未明。该文将重点介绍微生物菌群在胶质瘤中的相关研究进展并简要论述其在胶质瘤疾病进程中的作用机制，为深入探讨胶质瘤的发病机制以及改善治疗预后提供新的思路。

Abstract:

In recent years， the interplay between glioma and gut microbiota has gradually become a research hotspot， and some studies have found the existence of microbial flora in glioma. Although studies have revealed that gut microbiota may affect glioma through the mechanisms such as immunomodulation and epigenetic modification， the specific mechanism remains unclear. This article mainly introduces the research advances in microbial flora in glioma and elaborates on its mechanism of action in the progression of glioma， in order to provide new ideas for delving deeper into the pathogenesis of glioma and improving the treatment and prognosis of glioma.