缺血性卒中脑细胞保护临床实践中国专家共识

Chinese expert consensus on clinical practice for brain cytoprotection in ischemic stroke

摘要:

缺血性卒中后神经血管单元的全脑细胞保护是改善神经功能预后的关键策略。近30年来，全球学者通过基础研究、转化医学和临床试验的协同推进，促使脑细胞保护药物呈现多元化发展态势。为构建符合我国临床实际的脑保护治疗决策体系，专家组整合国内外最新研究成果、循证医学证据及专家意见，制定了符合我国实际情况的《缺血性卒中脑细胞保护临床实践中国专家共识》。该共识系统阐述了脑细胞保护治疗措施的选择、用药时机的把握，旨在为临床诊疗实践提供指导，促进脑细胞保护治疗的规范化和个体化，对改善患者神经功能转归具有重要指导价值。

Abstract:

Comprehensive cytoprotection of the neurovascular unit following ischemic stroke constitutes a pivotal strategy for improving neurological functional recovery. Over the past three decades， synergistic advancements in fundamental research， translational medicine， and clinical trials across the globe have driven diversified evolution of brain cytoprotective agents. To establish a decision-making framework for cytoprotective therapies tailored to China's clinical realities， the expert panel has integrated cutting-edge research findings， evidence-based medical data， and multidisciplinary expert insights from domestic and international sources， culminating in the establishment of the Chinese expert consensus on clinical practice for brain cytoprotection in ischemic stroke. This consensus systematically elaborates on the selection of brain cytoprotective interventions and optimal timing of therapeutic administration， aiming to provide guidance for standardized and personalized brain cytoprotection practice， which holds significant clinical value for optimizing the neurological outcomes of patients with ischemic stroke.