消化科首诊的抗SOX1抗体阳性副肿瘤性边缘叶脑炎1例

Paraneoplastic limbic encephalitis with positive anti-SOX1 antibody initially presenting to the department of gastroenterology: a case report

摘要:

副肿瘤性边缘叶脑炎常表现为认知障碍、精神行为异常、癫痫发作等症状，临床表现复杂多变，部分患者首诊于非神经科室。该文报道1例首诊于消化科的抗SOX1抗体阳性副肿瘤性边缘叶脑炎患者，并复习相关文献，分析临床及影像学特点，提高对抗SOX1抗体阳性副肿瘤性边缘叶脑炎的认知，尽早识别，以改善患者预后。

Abstract:

Paraneoplastic limbic encephalitis often manifests as cognitive impairment， psychiatric-behavioral abnormalities， and seizures， with complex and diverse clinical manifestations， and some patients attend non-neurological departments at the first consultation. This article reports a case of paraneoplastic limbic encephalitis with positive anti-SOX1 antibody initially presenting to the department of gastroenterology， and a literature review was also performed to analyze its clinical and imaging features， enhance the awareness of paraneoplastic limbic encephalitis with positive anti-SOX1 antibody， facilitate early identification， and thus improve the prognosis of patients.