基于Scopus数据库脑深部电刺激术与癫痫的文献计量学分析

A bibliometric analysis of deep brain stimulation and epilepsy based on Scopus database

摘要:

目的 基于Scopus数据库对脑深部电刺激（DBS）与癫痫研究进行文献计量学和可视化分析，为临床提供参考。方法 在Scopus中以“DBS与癫痫”为主题词检索1960年1月1日至2024年5月16日发表的文献，并用VOSviewer和R软件的Bibliometrix工具包进行文献计量学和可视化分析，分析研究现状和趋势。同时以Web of Science核心合集数据库对2004—2024年的文献进行验证。结果 共纳入Scopus数据库的2 322篇文献，DBS与癫痫研究领域近20年发文量占总数90%以上，美国文献发文量982篇，中国220篇，第3～第5位国家发文量均不足200篇。发文量最多的作者是Lozano Andres M。发表文献被引用前5位国家是美国、加拿大、英国、法国、德国，中国排在第8位。基于Bibliometrix，该研究领域相关度最高的前5个机构是首都医科大学、梅奥诊所、加利福尼亚大学、多伦多大学、浙江大学。期刊分布显示Epilepsia[影响因子（IF）=6.6]、Epilepsy & Behavior（IF=2.3）及Brain Stimulation（IF=7.6）构成该领域的核心传播平台。关键词共现分析表明，“DBS临床应用”“难治性癫痫”“神经调控机制”“刺激参数优化”及“性别差异”为当前五大研究热点。结论 美国在该研究领域贡献度及关联度排首位，中国在该研究领域也有较重要贡献。已形成以临床神经科学为核心，融合生物医学工程、计算神经科学及分子机制研究的复合型知识体系。刺激靶点选择标准、闭环神经调控系统开发及多中心随机对照试验设计将成为未来重点突破方向。

Abstract:

Objective To conduct bibliometric and visual analyses of deep brain stimulation （DBS） and epilepsy based on Scopus database， and to provide a reference for relevant personnel.Methods The Scopus database was searched for related articles published from January 1， 1960 to May 16， 2024 with the subject words of “DBS and epilepsy”， and VOSviewer and Bibliometrix toolkit of R software were used to perform the bibliometric and visual analyses and analyze the current status and trends of research. The Web of Science Core Collection （WoSCC） database was used to verify the articles in the past 20 years from 2004 to 2024.Results A total of 2 322 articles from the Scopus database were included for analysis， and the articles published in the last two decades accounted for more than 90% of the total articles published in the field of DBS and epilepsy， with the highest number of 982 publications in the US， followed by 220 publications in China， and fewer than 200 publications in the countries ranking third to fifth. Lozano Andres M. was the author with the highest number of publications. The top five countries in terms of citation were the US， Canada， the UK， France， and Germany， while China ranked eighth. Based on Bibliometrix， institutional collaboration networks identified Capital Medical University， Mayo Clinic， the University of California system， University of Toronto， and Zhejiang University as key knowledge hubs. The analysis of journals revealed Epilepsia （impact factor ［IF］ = 6.6）， Epilepsy & Behavior （IF=2.3）， and Brain Stimulation （IF=7.6） as the primary dissemination platforms. The keyword co-occurrence analysis showed that “DBS clinical applications”， “management of refractory epilepsy”， “neuromodulation mechanisms”， “optimization of stimulation parameters”， and “gender-specific outcomes” were the five research hotspots in this field.Conclusion The US has the highest degree of contribution and collaboration in this field， and China also has important contributions in this field. An interdisciplinary knowledge system has been established with clinical neuroscience as its core， integrating biomedical engineering， computational modeling， and molecular pathophysiology. Standardization of target selection criteria， development of closed-loop adaptive DBS systems， and design of multicenter randomized controlled trials will be important directions for further research.